Nikki Wong shares a love-hate on-off relationship with Jonesy. Following their almost first kiss they date for approximately three months during the second season until a series of events pushes Nikki to believe that, should they continue seeing each other, they will end up losing their friendship forever.
As a result, she convinces Jonesy to break up. Jonesy falls back into his old womanizing habits, however, while Nikki falls into a cycle of resentment and guilt. Ultimately, both admit their feelings for one another and commit to a serious relationship.
Nikki has furthermore dated Hunter, a sales associate at Albatross & Finch to whom Caitlin was also enthralled, as well as Stone, a worker at the Grind Me coffee shop, who resembled herself in terms of personality, she has also dated Jonesy Garcia and has broken up with him once.
Nikki is employed in the Galleria Mall at the Khaki Barn, along with co-workers Chrissy, Kirsten, and Kristen, who she refers to as "The Clones" and the Khaki Barn as the "Crappy Barn" and "Tacky Barn". She intends to save enough money to go traveling around the world. Nikki was temporarily fired once for revealing Chrissy's secret life as a member of the Jedi Knight Club – replaced by a more conformist girl, Ashley – and forced to work at the Stereo Shack electronics store with a Star Wars geek named Darth. In addition, she quit her job after being harassed by the Clones under suspicion of shoplifting, but returned when Chrissy offered her extended breaks and the opportunity to choose her own shifts. She and her parents move farther up north in the series finale. Despite this, she keeps in touch with her friends and she and Jonesy commit to a long-distance relationship.